From Wikipedia:
Lopez was married to Ali Landry for 2 weeks but the marriage ended on May 15, 2004. The marriage was annulled over alleged infidelities committed by Lopez during the relationship, and particularly the week leading up to the wedding. There have been rumors that Lopez is gay, to which he responded on Mind of Mencia by doing a Brokeback Mountain parody as well as a monologue about how it is not true.
Lopez was recently dating Karina Smirnoff. However, on June 4, 2008 Smirnoff confirmed that she and Lopez are no longer an item.
Lopez is an avid boxing fan. He was seen on camera during the Floyd Mayweather vs Ricky Hatton fight. He also commentates for Top Rank on overseas broadcasts of Manny Pacquiao fights.
Mario has a sister named Marissa, who is married to former NFL linebacker Kailee Wong.
He is still very good friends with fellow Saved by the Bell star and on-screen girlfriend Elizabeth Berkley, who came to support him while he was taking part in Dancing with the Stars.